Author

R. Siegel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

B. E. Griffith· 1 shared D. J. Blundon· 1 shared E. M. Kolahdouz· 1 shared J. C. Javitt· 1 shared J. W. Dutton· 1 shared L. N. Scotten· 1 shared M.-A. Deutsch· 1 shared R. Kumar· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

B. E. Griffith

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2 papers

Recent·Most cited

Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting

L. N. Scotten, R. Siegel, D. J. Blundon, M.-A. Deutsch, T. R. P. Martin, J. W. Dutton, E. M. Kolahdouz, B. E. Griffith

The paper links predicted blood shear forces during prosthetic valve closure to thrombogenicity, providing a metric to optimize valve designs for reduced thrombogenicity.

bioRxiv · Jun 23, 2022 · PreprintBioengineering

NRX-101, A RAPID-ACTING ANTI-DEPRESSANT, DOES NOT CAUSE NEUROTOXICITY FOLLOWING KETAMINE ADMINISTRATION IN PRECLINICAL MODELS

W. Jordan, R. Siegel, R. Kumar, J. C. Javitt

This study evaluates the neurotoxicity of NRX-101 (D-cycloserine/lurasidone) with and without ketamine in rats, finding no histologic neurotoxicity even at maximum doses.

bioRxiv · Jun 18, 2022Pharmacology & Toxicology