Author

R. Tching Chi Yen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

I. Ntafoulis· 2 shared S. Leenstra· 2 shared A. Biswas· 1 shared A. C. O'Farrell· 1 shared A. Idbaih· 1 shared A. Kremer· 1 shared A. T. Byrne· 1 shared C. Beerens· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

I. Ntafoulis

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2 papers

Recent·Most cited

Cancer BiologybioRxivAug 11, 2023

Identification of inter- and intra-tumoral molecular phenotypes steering temozolomide resistance in patient-derived glioblastoma cells.

F. Fabro, T. V. Kers, K. J. Feller…·S. Leenstra

This study identifies two molecular phenotypes, ADA and N-ADA, associated with temozolomide resistance in glioblastoma cells through bulk and single-cell RNA sequencing.

DOI 10.3390/ijms242115678

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 9, 2021

Generation, characterization and drug sensitivities of twelve patient-derived IDH1 mutant glioma cell cultures

C. Verheul, I. Ntafoulis, T. Kers…·M. Lamfers

The paper establishes twelve patient-derived IDH1 mutant glioma cell cultures, confirms their similarity to parental tumors, and identifies nine FDA-approved drugs with activity against IDH-mutant gliomas.

DOI 10.1101/2021.04.09.435131

humanbulk RNA-seq

𝕏 PostBluesky