The post-acute phase of SARS-CoV-2 infection in two macaques species is associated with signs of ongoing virus replication and pathology in pulmonary and extrapulmonary tissues
K. P. Boszormenyi, M. A. Stammes, Z. C. Fagrouch, G. Kiemenyi-Kayere, H. Niphuis, D. Mortier, N. van Driel, I. Nieuwenhuis, R. Vervenne, T. Haaksma, B. Ouwerling, D. Adema, R. F. Acar, E. Zuiderwijk-Sick, L. Meijer, , B. E. Verstrepen
This study shows that SARS-CoV-2 persists in multiple tissues and replicates in macaques during the post-acute phase, even after viral RNA is no longer detectable in nasal swabs.
bioRxiv · Nov 5, 2020Microbiology