A novel Hsp90 phospho-switch modulates virulence in the major human fungal pathogen Candida albicans
S. Diezmann, L. Alaalm, J. L. Crunden, M. Butcher, U. Obst, R. Whealy, C. E. Williamson, H. E. O'Brien, C. Schaffitzel, G. Ramage
This study identifies two Hsp90 phosphorylation sites in Candida albicans that modulate virulence by affecting stress response, morphogenesis, and drug susceptibility.
bioRxiv · Sep 23, 2020 · PreprintMicrobiology