Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
H. Arellano-Santoyo, R. A. Hernandez-Lopez, E. Stokasimov, R. Y. Wang, D. Pellman, A. E. Leschziner
This study identifies structural features of yeast kinesin-8 Kip3 that enable its switch between motility and MT depolymerization through cryo-EM and molecular dynamics simulations.
bioRxiv · Oct 12, 2021 · PreprintBiophysics