BIRC5 regulates the IGFBP-3-induced autocrine loop in cancer stem cells.
Y.-J. Kahm, U. Jung, R.-K. Kim
This study identifies BIRC5 as a key regulator of cancer stem cells and EMT, showing its role in promoting CSC characteristics and forming an autocrine loop with IGFBP-3.
bioRxiv · Mar 9, 2023 · PreprintCancer Biology