A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel
Wendy Guan, Kaidy G. Orellana, R.F. Stephens, Boris S. Zhorov, J. David Spafford
The paper shows that a lysine residue in a novel extracellular loop of T-type Cav3 channels determines ion preference by altering the interaction with a nearby aspartate residue.
bioRxiv · May 11, 2022 · PreprintNeuroscience