Developmental Progression and Single-Cell Heterogeneity of Orientia tsutsugamushi during Intracellular Infection
Chitrasak Kullapanich, Frances Aylward, Rachel Jackson, Jeanne Salje
This study identifies four distinct growth stages of Orientia tsutsugamushi within host cells using single-cell analysis, revealing asynchronous growth and transcriptional/translation heterogeneity.
bioRxiv · Dec 9, 2025 · PreprintMicrobiology