Genome-wide genetic risk for SLE and disease severity
Lingyan Chen, Yongfei Wang, Lu Liu, Adrianna M. Bielowka, Rahell Ahmed, Huoru Zhang, Phil Tombleson, Amy L. Roberts, Christopher A. Odhams, Deborah S. Cunninghame Graham, Xuejun Zhang, Wanling Yang, Timothy James Vyse, David Lester Morris
This study evaluates genetic risk scores for predicting SLE susceptibility and severity using GWAS data from European and Chinese populations, finding moderate predictive performance and associations with renal disease and age of onset.
Human Molecular Genetics · Feb 17, 2020Peer-reviewedGenetics