Cannabinoid inhibition of mechanosensitive K+ channels
Trevor A. Docter, Ben Sorum, Rahul Deshmane, Cody E. Doubravsky, Stephen Graf Brohawn
This study shows cannabinoids inhibit mechanosensitive K2P channels, including disease-causing mutants, and reveals the mechanism of channel block via CBD binding.
bioRxiv · Dec 9, 2024 · PreprintNeuroscience