Author
University of California, BerkeleyORCID 0000-0003-2647-9649Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Peter H. Yoon, Kenneth J. Loi, Zeyuan Terry Zhang…·Jennifer A. Doudna
The paper identifies VIPR systems, which use noncontiguous RNA codes for DNA recognition, suggesting an ancient origin of adaptive immunity through viral interactions.
Trevor A. Docter, Nicolas Sammy Lee, Michelle Reid, Stephen Graf Brohawn
This study determines the cryo-EM structure of TASK-1 at low pH and shows how protonation of an extracellular histidine leads to channel closure, with mutations affecting proton sensitivity.
Peter H. Yoon, Trevor A. Docter, Zeyuan Terry Zhang…·Jennifer A. Doudna
The paper reveals the structural mechanism of VIPR RNA-guided DNA recognition through triplex formation, showing how noncontiguous RNA sequences direct DNA targeting.
Trevor A. Docter, Ben Sorum, Rahul Deshmane…·Stephen Graf Brohawn
This study shows cannabinoids inhibit mechanosensitive K2P channels, including disease-causing mutants, and reveals the mechanism of channel block via CBD binding.
Fred Schwaller, Valérie Bégay, Gema García‐García…·Gary R. Lewin
This study shows that USH2A is essential for vibration sensing in mice and humans by being expressed in Meissner corpuscle end-organs, not in sensory neurons.