BRET-Based Ligand Binding at Recombinant and Endogenous Dopamine D2 Receptors
Kole Martin, Rajani Nimma, Takudzwa Mabvuta, Sandra Ortigueira, Eddy Sotelo, María Majellaro, Prashant Donthamsetti
The paper develops three far-red fluorescent antagonists as BRET tracers for D2R, enabling quantitative ligand binding measurements at recombinant and endogenous receptors.
bioRxiv · Oct 28, 2026 · PreprintPharmacology & Toxicology