Association of object mnemonic discrimination deficit with age and AD biomarkers in older adults
Zhengshi Yang, Xiaowei Zhuang, Lynn M. Bekris, Maria Khrestian, Katherine A. Koenig, Tim Curran, Rajesh Nandy, Pavithran Pattiam Giriprakash, Chendi Han, Jagan Pillai, Robert Fox, Mark J. Lowe, Dietmar Cordes
This study links object mnemonic discrimination to age and AD biomarkers in older adults, finding strong associations with hippocampal volume and pTau217, and comparable diagnostic accuracy to established biomarkers.
bioRxiv · Sep 17, 2026 · PreprintNeuroscience