Cancer BiologyBiochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsPeer-reviewed
DDX5 (p68) orchestrates β-catenin, RelA and SP1 mediated MGMT gene expression: Implication in TMZ chemoresistance
Rajni Shaw, Subhajit Karmakar, Malini Basu, Mrinal K. Ghosh
This study identifies DDX5 (p68) as a master regulator of MGMT gene expression through interactions with β-catenin, RelA, and SP1, contributing to TMZ chemoresistance in colon cancer.
7 citations