Affinity-tag-based microfluidic protein isolation enables high-resolution Cryo-EM from minimal starting material
Michael Zimmermann, Dorothee Elaine Schneider, Luca Rima, Thomas Clairfeuille, Ralf Thoma, Matthias E. Lauer, Thomas Braun
This paper introduces a microfluidic method for isolating tagged proteins from small samples, enabling high-resolution Cryo-EM with reduced volume and time requirements.
bioRxiv · May 28, 2026 · PreprintMolecular Biology