Cross-Modal Training Using Xenium Spatial Transcriptomics Enables DINO-DETR Based Detection of Vascular Niches in H&E Whole-Slide Images
Pranali Sonpatki, Ramya Alugam, Shashank Gupta, Nameeta Shah, Megha S. Uppin
This paper develops a DINO-DETR model trained on spatial transcriptomics data to detect vascular niches in H&E slides, showing improved vascular quantification and prognostic value in astrocytoma.
bioRxiv · Mar 19, 2026 · PreprintPathology