Endoplasmic Reticulum Associated Lipolysis Regulates Hepatic Fat Synthesis and Turnover
Jihong Lian, Russell Watts, Randal Nelson, John Paul Kennelly, Aducio Thiesen, Ariel D. Quiroga, Donna Faye Vine, Robin D. Clugston, René L. Jacobs, Richard S. Lehner
This study identifies AADAC as a regulator of hepatic lipid metabolism, showing its role in suppressing lipid synthesis and preventing MASLD under overnutrition.
bioRxiv · May 12, 2026 · PreprintPhysiology