Disruption of the grid cell network in a mouse model of early Alzheimer's disease
Johnson Ying, Alexandra T. Keinath, Raphael Lavoie, Érika Vigneault, Salah El Mestikawy, Mark P. Brandon
This study shows that in a mouse model of early Alzheimer's disease, grid cells in the medial entorhinal cortex show impaired spatial coding, coinciding with early Aβ fibril deposition and spatial memory deficits.
Nature Communications · Feb 16, 2022Peer-reviewedNeuroscience