Mark P. Brandon

This study identifies medial septal glutamatergic neurons as essential for maintaining grid cell spatial stability and speed coding in the medial entorhinal cortex through optogenetic silencing and network modeling.

The paper investigates sex differences in processing negative social valence using social valence tasks and in vivo calcium imaging in mice, finding females show reduced identity recognition in negative social contexts.

This study shows that hippocampal reward representations become predictive of reward over time as mice learn a reward-based task.

The paper identifies representational structure in CA1 remapping across brains and benchmarks cognitive mapping models against observed neuronal dynamics.

The paper identifies a direct projection from the anterior dorsal thalamus to VIP-expressing interneurons in the medial entorhinal cortex, which are critical for spatial memory.

This study investigates how neural representations in the ventral hippocampus (vCA1) change during fear memory tasks and finds that representational similarity in vCA1 supports faster context retrieval.

The paper investigates grid cell impairments in a mouse model of early Alzheimer's disease, finding reduced integration of self-motion cues and altered spatial coding patterns.

This study shows that REM sleep stabilizes newly formed place cells through coordinated population activity in the hippocampus.

This study shows that working memory does not require a single time cell sequence during the delay period, as optogenetic reduction of theta oscillations led to remapping and new sequences without affecting behavior.

This study shows that in a mouse model of early Alzheimer's disease, grid cells in the medial entorhinal cortex show impaired spatial coding, coinciding with early Aβ fibril deposition and spatial memory deficits.

This study investigates how the thalamic head direction system adapts to environmental cues through dynamic population dynamics and memory mechanisms.

This study characterizes the electrophysiological, morphological, and input properties of VIP interneurons in the MEC of mice, revealing their sensory inputs and role in disinhibition.

This study shows that long-term changes in the CA1 spatial code maintain the relative structure of contextual representation over weeks.

The paper introduces a standardized platform for high-throughput imaging of neuronal dynamics during behavior in mice and marmosets.

The paper shows that DG-CA3 circuitry is essential for maintaining latent information representations in the hippocampus during navigation.

The paper introduces a zero-inflated gamma model for deconvolved calcium imaging traces, showing it outperforms simpler models in simulated and real neural data.