Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation.
Floris Bosveld, Baptiste Tesson, Eric van Leen, Sam Amirebrahimi, Raphael Thinat, Yohanns Bellaı̈che
The paper investigates how epithelial tissues maintain architecture and cell number despite spindle misorientation, identifying mechanical and systemic signaling mechanisms that prevent cell loss.
Developmental Cell · Feb 16, 2026Peer-reviewedDevelopmental Biology