A microbiota-dependent gut bile acid axis links germline mutant p53 to distal tumour growth.
Noel Ong, Nicholas William Fischer, Camilla Giovino, Paula Rosanna Quaglietta, Y.H. Park, Raya Traubici, David M. Malkin
This study shows that mutant p53 alters gut microbiota interactions, leading to bile acid changes that promote distal tumour growth.
bioRxiv · Oct 6, 2026 · PreprintCancer Biology