Author

Nicholas William Fischer

Hospital for Sick ChildrenORCID 0000-0003-4672-0532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

David M. MalkiniD· 2 shared Amina AmadouiD· 1 shared Arnold J. LevineiD· 1 shared Camilla Giovino· 1 shared Catherine GoudieiD· 1 shared Christian Peter KratziD· 1 shared Claire FreyçoniD· 1 shared Emilie MontellieriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

David M. MalkinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 6, 2026

A microbiota-dependent gut bile acid axis links germline mutant p53 to distal tumour growth.

Noel Ong, Nicholas William Fischer, Camilla Giovino…·David M. Malkin

This study shows that mutant p53 alters gut microbiota interactions, leading to bile acid changes that promote distal tumour growth.

DOI 10.64898/2026.10.05.753853

mousemetabolomics

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Genetic & Genomic MedicineiSciencePeer-reviewedNov 1, 2024

Fine resolution clustering of TP53 variants into functional classes predicts cancer risks and spectra among germline variant carriers

Emilie Montellier, Nathanaël Lemonnier, Judith Penkert…·Pierre L. Hainaut

30 citationstop 3%

humanDNA methylation

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