Confident Identification and Quantification of Mouse Brain Tissues Reveals Sirtuin 5-Dependent Regulation
Jorge Landgrave-Gómez, Joanna Bons, Genesis Vega Hormazabal, Rebecah Riley, Birgit Schilling, Eric Verdin
This paper develops a proteomic workflow to confidently identify and quantify lysine methylmalonylation in mouse brain tissue, revealing its regulation by SIRT5 and its role in myelin stability.
bioRxiv · May 28, 2026 · PreprintCell Biology