Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43 acts on the catalytic snRNA U6
Rebecca Toroney, Klaus H. Nielsen, Jonathan P. Staley
The paper identifies the role of Prp43 in splicing termination by interacting with the 3-end of U6 snRNA, revealing a mechanism for spliceosome disassembly and substrate release.
bioRxiv · Jun 4, 2019Molecular Biology