Author

Rebekah Kember

Hospital for Sick Children

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Genetics· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Dhekra Al-BashaiD· 1 shared Dwi U. KemaladewiiD· 1 shared Elzbieta HyattiD· 1 shared Evgueni A. IvakineiD· 1 shared Kara M. Place· 1 shared Kinga I. GawlikiD· 1 shared Kyle Lindsay· 1 shared Madeleine DurbeejiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Dhekra Al-BashaORCID

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1 paper

Recent·Most cited

A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo.

Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Elzbieta Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn

This paper demonstrates that upregulating a disease modifier gene using CRISPR/dCas9 can rescue muscular dystrophy in mice, showing that muscle fibrosis may be reversible.

Nature · Jul 24, 2019Peer-reviewedGenetics