Structural Basis for Retron Co-option of Anti-phage ATPase-nuclease
Bing Wang, Renee D. Hoffman, Ya‐Ming Hou, Hong Li
This study determines the structural basis of how Ec78 retrons co-opt the PtuAB ATPase-nuclease system for anti-phage defense through cryo-EM and biochemical analysis.
Nature Structural & Molecular Biology · Oct 31, 2025Peer-reviewedBiophysics