Combinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
Svetlana Panina, Seema Irani, Haley A. Hardtke, Renee Stephenson, Brendan M. Floyd, Rosamaria Y. Moreno, Edward M. Marcotte, Qian Zhang, Yan Zhang
The paper develops a method to detect combinatorial phosphorylation patterns on RNA polymerase II CTD and shows they recruit TREX for mRNA processing and export.
bioRxiv · Jan 13, 2025 · PreprintMolecular Biology