EnSEMBLE: a framework for enhancer-anchored pathway analysis that locks in enhancer-corroborated pathways from transcriptome sequencing data for biological validation
Laizhi Zhang, Akshat Gupta, Yue Wang, Renu Sharma, Bashir Lawal, Gavin Hou, Xiao‐Song Wang
EnSEMBLE reduces redundant gene sets to enhancer-corroborated pathways by integrating enhancer RNA data with pathway enrichment analysis, improving biological relevance and reducing false positives.
bioRxiv · Aug 21, 2026 · PreprintBioinformatics