Author

Xiao‐Song Wang

University of PittsburghORCID 0000-0002-2570-7139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Yue WangiD· 3 shared Sanghoon LeeiD· 2 shared Akshat GuptaiD· 1 shared Bashir LawaliD· 1 shared Gavin HouiD· 1 shared Gong TangiD· 1 shared Han ZhangiD· 1 shared Kai WangiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Yue WangORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 21, 2026

EnSEMBLE: a framework for enhancer-anchored pathway analysis that locks in enhancer-corroborated pathways from transcriptome sequencing data for biological validation

Laizhi Zhang, Akshat Gupta, Yue Wang…·Xiao‐Song Wang

EnSEMBLE reduces redundant gene sets to enhancer-corroborated pathways by integrating enhancer RNA data with pathway enrichment analysis, improving biological relevance and reducing false positives.

DOI 10.64898/2026.08.17.745283

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintAug 28, 2022

IndepthPathway: an integrated tool for in-depth pathway enrichment analysis based on bulk and single cell sequencing data.

Sanghoon Lee, Letian Deng, Yue Wang…·Xiao‐Song Wang

IndepthPathway improves pathway enrichment analysis for single-cell and bulk RNA-seq by addressing noise and low coverage issues through the WCSEA algorithm.

DOI 10.1101/2022.08.28.505179

bulk RNA-seqscRNA-seq

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BioinformaticsNature CommunicationsPeer-reviewedMay 26, 2022

An integral genomic signature approach for tailored cancer targeted therapy using genome-wide sequencing data

Xiao‐Song Wang, Sanghoon Lee, Han Zhang…·Yue Wang

This paper introduces iGenSig, a genomic signature method for predicting cancer therapy responses using genome-wide sequencing data, showing strong cross-dataset performance and resilience to sequencing errors.

15 citations

humanwhole-genome sequencing

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