BioinformaticsbioRxivPreprint
EnSEMBLE: a framework for enhancer-anchored pathway analysis that locks in enhancer-corroborated pathways from transcriptome sequencing data for biological validation
Laizhi Zhang, Akshat Gupta, Yue Wang…·Xiao‐Song Wang
EnSEMBLE reduces redundant gene sets to enhancer-corroborated pathways by integrating enhancer RNA data with pathway enrichment analysis, improving biological relevance and reducing false positives.
DOI 10.64898/2026.08.17.745283