Inducible and reversible phenotypes in a novel mouse model of Friedreich’s Ataxia
Vijayendran Chandran, Kun Gao, Vivek Swarup, Revital Versano, Hongmei Dong, Maria C. Jordan, Daniel H. Geschwind
This study develops an inducible mouse model of Friedreich’s Ataxia to investigate reversible phenotypes by modulating frataxin levels and observing functional recovery.
eLife · Dec 19, 2017Peer-reviewedNeuroscience