Membrane proteins ClcB, PtsI and YcaM mediate the bactericidal effects of colistin in Escherichia coli
Rhys Donafee, Mohammad S. Radi, Douglas Bruce Kell, Jesus Enrique Salcedo-Sora
The paper identifies three membrane proteins in E. coli that mediate colistin's bactericidal effects, showing their role in the cytotoxic pathway following polymyxin membrane disruption.
ACS Infectious Diseases · Oct 30, 2025Peer-reviewedMicrobiology