NeuroscienceNeurobiology of AgingPeer-reviewed
Advanced age attenuates the antihyperalgesic effect of morphine and decreases μ-opioid receptor expression and binding in the rat midbrain Periaqueductal Gray in male and female rats
Evan F. Fullerton, Myurajan Rubaharan, Mary C. Karom…·Anne Z. Murphy
This study shows that aging reduces morphine's pain-relieving effect and lowers μ-opioid receptor levels in the rat midbrain PAG, affecting both males and females.
12 citations