Genetic evidence for a periplasmic protein as a component for a subset of NtrYX two-component systems
Alexa R. Wolber, Liliana S. McKay, Richard M. Johnson, Zain T. Hameed, Katlyn B. Mote, Steven M. Julio, Peggy A. Cotter
The paper identifies PlrP as an essential third component of the PlrSR two-component system in Bordetella species, showing it inhibits PlrS phosphatase activity and is required for in vivo survival.
bioRxiv · Nov 7, 2025 · PreprintMicrobiology