ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions
Haythem Latif, Stephen Federowicz, Ali Ebrahim, Janna Tarasova, Richard Szubin, Jose Utrilla, Karsten Zengler, Bernhard Palsson
This study uses ChIP-exo to analyze Crp, DNA, and RNAP holoenzyme interactions, finding Crp does not protect the DNA motif but shows binding patterns similar to σ70, suggesting it dissociates post-recruitment during transcription initiation.
PLOS ONE · May 17, 2018Peer-reviewedMolecular Biology