Author

Stephen Federowicz

Ideaya Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ali Ebrahim· 1 shared Andrea L. Halweg‐EdwardsiD· 1 shared Andrew D. GarstiD· 1 shared Bernhard Palsson· 1 shared Bryan A. Leland· 1 shared Chad D. Sanada· 1 shared Charlie Johnson· 1 shared Christopher G. Abraham· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Ali Ebrahim

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A framework for evaluating edited cell libraries created by massively parallel genome engineering

Simon E. Cawley, Eric Abbate, Christopher G. Abraham, Steven Alvarez, Mathew Barber, Scott Bolte, Jocelyne Bruand, Deanna M. Church, Clint Davis, Matthew Estes, Stephen Federowicz, Richard J. Fox, Miles W. Gander, Andrew D. Garst, Gozde Gencer, , Michael S. Graige

The paper introduces a framework for evaluating edited cell libraries generated by genome engineering, defining metrics and connecting analysis to phenotyping approaches.

bioRxiv · Sep 23, 2021 · PreprintGenomics

ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions

Haythem Latif, Stephen Federowicz, Ali Ebrahim, Janna Tarasova, Richard Szubin, Jose Utrilla, Karsten Zengler, Bernhard Palsson

This study uses ChIP-exo to analyze Crp, DNA, and RNAP holoenzyme interactions, finding Crp does not protect the DNA motif but shows binding patterns similar to σ70, suggesting it dissociates post-recruitment during transcription initiation.

PLOS ONE · May 17, 2018Peer-reviewedMolecular Biology