Sequencing-free Tissue-wide Spatial Profiling of Post-transcriptional Regulations
Xianglin Ji, Peilin Fang, Xi Zhao, Chuanyin Xiong, Qi Yang, Youyang Wan, Richard Yan, Zixun Wang, Lin Qi, Linfeng Huang, Wenjun Zhang, Xin Wang, Peng Shi
This paper introduces a sequencing-free technique called Spectrum-FISH to profile post-transcriptional regulations in tissue sections with high throughput and spatial resolution, showing spatial heterogeneity in miRNAs and m6A-mRNAs in rodent olfactory bulb.
bioRxiv · Dec 11, 2022 · PreprintGenomics