Lin Qi

FFPERescuer: deep unsupervised domain adaptation for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples

FFPERescuer uses deep learning to improve gene expression reconstruction from degraded FFPE samples, achieving high accuracy and enhancing cancer subtyping.

The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons

The paper investigates m1A RNA modification in neurons under normal and OGD/R conditions, identifying its regulatory roles in noncoding RNAs and ceRNA mechanisms.

Sequencing-free Tissue-wide Spatial Profiling of Post-transcriptional Regulations

This paper introduces a sequencing-free technique called Spectrum-FISH to profile post-transcriptional regulations in tissue sections with high throughput and spatial resolution, showing spatial heterogeneity in miRNAs and m6A-mRNAs in rodent olfactory bulb.

Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

This paper genomically characterizes 261 pediatric cancer patient-derived xenograft models to guide rational clinical trial design and drug development.