Time-resolved function of cell polarity kinases PRKCZ and PRKCI in CNS myelination
María Elisa Mercau, Rieke-Marie Hackbarth, Xinran Liu, Haowei Wang, Le Zhang, Malay Kumar Basu, Carla Vanina Rothlin, Sourav Ghosh
This study investigates the distinct roles of PRKCZ and PRKCI in oligodendrocyte differentiation and myelination, showing non-redundant functions in early specification and later maturation stages.
bioRxiv · Apr 22, 2024 · PreprintDevelopmental Biology