Noncanonical activation of Protease-activated receptor 1 induces autophagy in mammalian breast cancer cells
Saibal Saha, Rekha V. Kumar, Snehanjan Sarangi, Animesh Gope, Ananda Pal, Rima Tapader, Niraj Nag, Amit Pal
This study shows that noncanonical PAR1 activation by HAP induces autophagy in breast cancer cells, which inhibits tumor growth and delays carcinogenesis in a mouse model.
bioRxiv · Jan 11, 2025 · PreprintCancer Biology