Cell BiologyEMBO ReportsPeer-reviewed
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.
Marisa Bedir, Emily A. Outwin, Rita Colnaghi…·Mark O’Driscoll
This paper identifies a novel role for Cyclophilin A in DNA repair via interaction with the MRN complex, showing that its PPI activity is critical for homologous recombination repair after replication fork stalling.
6 citations