Transcriptomic profiling of plaque psoriasis and cutaneous T cell subsets during treatment with secukinumab
Jared Liu, Hsin-Wen Chang, Robby Grewal, Daniel D. Cummins, Audrey Bui, Kristen M. Beck, Sahil Sekhon, Di Yan, Zhiming Huang, Timothy H. Schmidt, Eric Yang, Isabelle M. Sanchez, Mio Nakamura, Shrishti Bhattarai, Quinn G. Thibodeaux, , Wilson J. Liao
This study examines the effects of secukinumab on transcriptomic changes in psoriatic skin and T cell subsets over 12 weeks, showing significant reduction in IL17A and related genes.
JID Innovations · Dec 30, 2021Peer-reviewedGenomics