Loss of circulating glucocorticoid rhythm disrupts the circadian transcriptome and vascular reactivity in the mouse renal artery
Georgios Krilis, Hannah M. Costello, Frances S Turner, Robert Little, Anastasiia Komolova, Josselin Nespoux, Alicja Czopek, Donald R. Dunbar, Matthew A. Bailey, Jessica Ruth Ivy
This study shows that disrupting the glucocorticoid rhythm in mice impairs circadian vascular function and alters the renal artery transcriptome, with implications for cardiovascular risk.
Cardiovascular Research · Nov 17, 2025Peer-reviewedPhysiology