Jessica Ruth Ivy

This study shows that disrupting the glucocorticoid rhythm in mice impairs circadian vascular function and alters the renal artery transcriptome, with implications for cardiovascular risk.

This study identifies CBR1 as a regulator of blood pressure in Down Syndrome, showing that its inhibition can increase blood pressure in a DS mouse model.

This study shows that Cushing Syndrome in mice causes impaired renal pressure natriuresis, altered blood pressure regulation, and salt-sensitivity.

The paper constructs a computational model of the mammalian renal circadian clock and validates it against experimental data to understand its role in blood pressure regulation.