Whole genome functional characterization of RE1 silencers using a modified massively parallel reporter assay
Kousuke Mouri, Hannah B. Dewey, Rodrigo Castro, Daniel Berenzy, Susan Kales, Ryan Tewhey
The paper identifies 1,500 human variants affecting RE1 silencers using a modified MPRA assay and shows how REST binding motifs influence silencing.
Cell Genomics · Dec 16, 2022Peer-reviewedGenomics