Hannah B. Dewey

The study examines how genetic variation in mouse induced pluripotent stem cells affects gene expression and cell cycle responses to triphenyl phosphate exposure.

The paper describes a panel of genetically diverse embryonic stem cells from Diversity Outbred mice to study natural genetic variation's impact on pluripotency and differentiation.

The paper generates a genetically diverse panel of iPSCs from a mouse population and identifies regulatory loci influencing gene expression variation.

This study functionally characterizes 221,412 trait-associated variants using MPRA in 5 cell types, identifying 12,025 regulatory variants and revealing widespread epistasis and non-TF mechanisms.

QTLretrievR simplifies molecular QTL identification in genetically diverse populations by integrating existing tools with parallelization, reducing computational time and improving accessibility.

The paper identifies eQTL in mouse neural progenitor cells and shows their effects on gene regulation across developmental stages.

The paper identifies 1,500 human variants affecting RE1 silencers using a modified MPRA assay and shows how REST binding motifs influence silencing.