Chemogenetic Activation of Medial Prefrontal Cortex Projections to the Nucleus Accumbens Shell Suppresses Cocaine-Primed Reinstatement in EcoHIV Infected Mice
Qiaowei Xie, Mark D. Namba, Rohan Dasari, Lauren A. Buck, Christine M Side, Samuel L. Goldberg, Kyewon Park, Joshua G. Jackson, Laura L. Giacometti, Jacqueline M. Barker
This study shows that HIV infection increases cocaine-primed reinstatement in mice and that activating the mPFC-NAc circuit can reverse this effect.
Psychopharmacology · Jul 16, 2025Peer-reviewedAnimal Behavior & Cognition