Paternal folate deficiency reveals meiosis as a metabolic sensing window in the male germline
Jasmine M. Esparza, Rohan V Kumar, Mengwen Hu, Yasuhisa Munakata, Saanvi Jain, Akihiko Sakashita, So Maezawa, Richard M. Schultz, Satoshi H. Namekawa
The paper shows that paternal folate deficiency affects meiotic chromatin and epigenomic changes in the male germline, particularly at CGI-associated promoters.
bioRxiv · Apr 26, 2026 · PreprintDevelopmental Biology