Author

Rohit Krishan Arora

Harvard University

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Bioinformatics· 1

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

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Debora S. MarksiD· 1 shared George McDonald ChurchiD· 1 shared Leo Tianlai Chen· 1 shared Melissa Du· 1 shared

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Debora S. MarksORCID

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1 paper

Recent·Most cited

PG-LLM: Benchmarking General-Purpose Language Models for Protein Variant Ranking

Rohit Krishan Arora, Leo Tianlai Chen, Melissa Du, Debora S. Marks, George McDonald Church

PG-LLM benchmarks language models for protein variant ranking, showing they outperform many sequence-based predictors but fall short of specialized models.

bioRxiv · Aug 21, 2026 · PreprintBioinformatics