Endogenous variability in transcription factor concentrations shapes their genome-wide occupancy
Romane Mizeret, Armelle Tollenaere, Cédric Deluz, David M. Suter
The paper investigates how fluctuations in OCT4, SOX2, and NANOG concentrations affect their genomic binding in mouse embryonic stem cells, revealing distinct concentration-dependent behaviors.
bioRxiv · Sep 24, 2025 · PreprintGenomics